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SIMPLE ECONOMICAL NONSURGICAL PREVENTION OF CATARACT INST DEVELOPED BY SCIENTISTS

SIMPLE ECONOMICAL NONSURGICAL PREVENTION OF CATARACT INST DEVELOPED BY SCIENTISTS

Context

Institute of Nano Science & Technology has developed nanorods from the nonsteroidal anti-inflammatory drug (NSAID) Aspirin to prevent cataract.

Details

  • Aspirin nanorods prevent the aggregation of crystallin protein and various peptides derived from its fragmentation, which play a crucial role in cataract formation.
  • It prevents the protein/peptide aggregation through biomolecular interactions, which convert beta-turn like the structure of the crystalline peptides, responsible for amyloid formation into coils and helices, those fail to aggregate.
  • The targeted disaggregation of the accumulated alpha-crystallin protein and crystallin derived peptide aggregates in aged and cataractous human lenses are considered as a viable therapeutic strategy for the prevention of cataract formation.

About Cataract

  • It is an opacification of the lens of the eye which leads to a decrease in vision.
  • It begins when proteins in the eye form clumps that prevent the lens from sending clear images to the retina.

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